Part II: All about the hormones (updated at the end)

on Sunday, June 10, 2012
Again, it does not *look* like a super pretty cycle that I am trying in. Its CD15 today.  I'm coming up to a surge possibly tomorrow. I picked this cycle because my Clear Blue Easy fertility monitor(CBEFM) switched to 'high' fertility a possible 4 days before ovulation, which is not too shabby.  To try to understand what that meant, I read the original studies looking up how the monitor works: There are 3 forms of estrogen: estradiol (strongest), estrone (middle strength) and estriol (weakest). The CBEFM measures the levels of a Estrone metabolite, which correlates very well to blood estradiol levels.  At some point, when the estrone levels increase past a certain threshold, the monitor changes from 'low' to 'high' fertility.

The good news, I've had 'high' fertility for around 3 days now, but the bad news is I have not seen a peep of the egg white CM yet.Apparently, estradiol (the strongest estrogen) drives the cervical mucous production. So when that gets super high, you get all that goopy stuff. It should be straightforward (lots of estradiol = lots of CM), but I have to wonder. Here is a question for you IVF ladies: There are times your estradiol levels must have gone through the roof, given the multiple maturing follicles: Do you always see the fertile CM during this time?


Because I've seen no CM yet, I was hoping  that ovulation would be delayed a day past CD17, but no dice, I've been monitoring my LH for the past 2 days, its on the rise and I think I should be in full surge by tomorrow (CD16). Which means the IUI is dayafter. ULP.

I am going in for hormonal monitoring and a U/S tomorrow. I have a feeling my stats (hormone levels, follicle sizes etc) are going to be very similar to my last cycles, and are considered bang normal by any RE, so my nitpicking and worry, is really for nothing. Something I cannot put my finger on is the problem.

In the last cycle, which was a BFN, I had a lot more 'symptoms' in the luteal phase which could
a) have been the result of a hypersensitive, far too imaginative psyche because absolutely nothing happened
b) been indicative of an embryo that probably bounced around for a few days, produced a smidgeon of HCG, before dying out because it could not implant, either due to uterine issues or because it was itself crappy quality and ran out of steam. Yeah- this covers most bases.

CD16 Testing and monitoring update:
EWCM made its exuberant entrance this morning (It always makes me SO happy to see it, yeah, I'm a little nuts but I blame this process :-))
U/S Monitoring:  The action is all in the left ovary (UGH- I have a hate-hate relationship with the left side of my body, will explain why sometime). Lining = 8.6 mm and 'beautiful'; Follicle = 17 mm (almost exactly the same as the last 2 times, albeit those measurements were on the day of ovulation, not from the day before).
Estrogen = 221 pg/ml-- normal for a single follicle,  I'm hoping it will be up a little tomorrow.

LH test results:
9 am blood work shows LH = 13. ie, looks like the surge is starting, but not there yet. 
2 pm check by OPK: Surge still not underway,  test line lighter than control.
7 pm check by OPK: LH surge is here. Test line now as dark as control.

IUI will be tomorrow. While I can apparently take a lot of shit and keep on going with barely a hitch in my stride, here is hoping the universe hands me something good instead.

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